George Husmann emigrated from Germany to Hermann, Missouri in 1839, and would soon become the preeminent 19th Century expert on America's grapes and wines. Husmann was instrumental in the development of both the Missouri and California grape industry.

Hermann Farm Museum is located on the same property where Husmann lived and operated Hermann Nurseries from 1851 to 1868. The grand residence where he lived and worked still stands and has recently been restored to its original grandeur. Carefully selected period furnishings recreate the look of the interior of the house during this time period. This building is called the Teubner-Husmann House, as Carl Teubner built the house when he married George Husmann's older sister. Husmann took over the complex several years later upon the untimely death of Teubner. The original farm outbuildings have also been restored and authentically represent the outside environment as it would have looked in the mid-1800s.

Hermann Farm is also home to the majestic Shire draft horses. These beautiful animals are the largest of the draft workhorses but are "gentle giants. White Missouri mules, named Pat and Jane, are also a hit with visitors.

Hermann Farm Museum is operated by Dierberg Educational Foundation, a 501(c)(3) charitable foundation dedicated to preserving and presenting the History and Heritage of the Missouri River Valley.